SIRT6 antibody (C-Term)

Catalog No. ABIN6147800

This anti-SIRT6 antibody is a Rabbit Polyclonal antibody detecting SIRT6 in WB. Suitable for Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for SIRT6 antibody (C-Term) (ABIN6147800)

Target: SIRT6 (Sirtuin 6 (SIRT6))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIRT6 Antibody

Binding Specificity: C-Term

Sequence: NLQPTKHDRQ ADLRIHGYVD EVMCRLMKHL GLEIPAWDGP CVLDKALPPL PRPVALKAEP PVHLNGAVHV SYKSKPNSPI LHRPPKRVKT EAAPS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse SIRT6 (NP_001156902.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-SIRT6 antibody (ABIN6147800)

Zhu, Yan, Shao, Tian, Zhou: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." in: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).

Target Details for SIRT6

Target: SIRT6 (Sirtuin 6 (SIRT6))

Alternative Name: SIRT6

Background: This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.,SIRT6,SIR2L6,sirtuin 6,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Deacetylation,SIRT6

Molecular Weight: 36 kDa/39 kDa

Gene ID: 50721

UniProt: Q8N6T7